Sigma-Aldrich Beclin-1 Activator I Tat-B

Product Name

Beclin-1 Activator I, TAT-Beclin-1, Scrambled, null

Assay

≥95% (HPLC)

Quality Level

100

Form

powder

Manufacturer/Tradename

Calbiochem^®

Storage Condition

OK to freeze
desiccated (hygroscopic)
protect from light

Color

white

Solubility

water: 25 mg/mL

Storage Temp.

2-8°C

General Description

A randomly shuffled Beclin-1 (267-284) peptide made cell-permeable by covalently attaching to HIV-1 Tat protein transduction domain via a diglycine linker. Reported to serve as a suitable control for autophagy-inducing peptides (Cat. nos. 506048 & 506416).A randomly shuffled Beclin-1 (267-284) peptide made cell-permeable by covalently attaching to HIV-1 Tat protein transduction domain via a diglycine linker. Reported to serve as a suitable control for autophagy-inducing peptides (Cat. nos. 506048 & 506416).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

Biochem/Physiol Actions

Cell permeable: yesReversible: yes

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Sequence

H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Gly-Gly~Val-Gly-Asn-Asp-Phe-Phe-Ile-Asn-His-Glu-Thr-Thr-Gly-Phe-Ala-Thr-Glu-Trp-OH

Other Notes

Liu, Y., et Al. 2013.Proc. Natl. Acad. Sci. USA 110,20364.
Shoji-Kawata, S., et Al. 2013.Nature. 494,201.CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany