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Sigma-Aldrich VITAMIN B12A HYDROCHLORIDE
List Price $148.48 Your Price $148.48
Sigma-Aldrich Vitamin B12a hydrochloride, ≥96% (UV), ≥96% (HPLC), 250 mg - SIAL (Additional S&H or Hazmat Fees May Apply)
NETA PART: SIAL-95200-250MG
MFG.PART: 95200-250MG
UNSPSC: 41122409
Manufacturer: Sigma-Aldrich
| biological source | |
|---|---|
fermentation/recombinant |
| Quality Level | |
|---|---|
100 |
| assay | |
|---|---|
≥96% (HPLC) |
| form | |
|---|---|
powder or crystals |
| loss | |
|---|---|
≤12% loss on drying, 20 °C (HV) |
| color | |
|---|---|
red to dark red |
| solubility | |
|---|---|
methanol: 10 mg/mL at 20 °C, clear, dark red |
| storage temp. | |
|---|---|
2-8°C |
| SMILES string | |
|---|---|
Cl.C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2N([Co+]O)C1=C(C)C3=NC(=CC4=NC(=C(C)C5=N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78 |
| InChI | |
|---|---|
1S/C62H90N13O14P.ClH.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H;;1H2/q;;+3;/p-3/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;;/m1.../s1 |
| Application | |
|---|---|
Biochem/physiol ActionsVitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine. |
| SKU | SIAL-95200-250MG |
|---|---|
| Supplier Part Number | 95200-250MG |
| UM | EA |
| UNSPSC | 41122409 |
| Manufacturer | Sigma-Aldrich |
| Temperature | 2-8C |
| Refrigerated-Frozen | Y |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Hazardous | N |
| CAS Number | 59461-30-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |