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Circadian Locomotor Output Cycles Kaput, or Clock is a gene which encodes proteins regulating circadian rhythm. This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like protein to activate transcription of mouse period 1.
Product Information
Format
Serum
Control
L6 Cell Lysate.
Presentation
Serum with 0.05% NaN3
Quality Level
MQ100
Applications
Application
Anti-CLOCK Antibody is an antibody against CLOCK for use in WB.
Key Applications
Western Blotting
Application Notes
Western Blot Analysis: L6 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-CLOCK (1:500 dilution of this lot). Proteins were visualized using a Donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system.
Biological Information
Immunogen
Recombinant Protein
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
Cat. # AB2203 recognizes CLOCK protein
Species Reactivity
Mouse
Rat
Human
Species Reactivity Note
Mouse, Human and Rat. Reactivity with other species has not been tested.
Antibody Type
Polyclonal Antibody
Gene Symbol
EC 2.3.1.48
KAT13D
KIAA0334
OTTHUMP00000128334
UniProt Number
AAC53200
Molecular Weight
Approx. 95 kDa
Product Usage Statements
Quality Assurance
Routinely evaluated by western blot on L6 tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt.
