The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
NETA ALERT: Due to inclement weather our offices are closed today, Monday Feb. 23. We will not be shipping orders.
Millipore Anti-Lyar Antibody (Ly1 Reactive Clone) Detects Level Of Lyar (Ly1 Antibody Reactive Clone) & Has Been Published & Validated For Use In Wb. - Mill (Additional S&H or Hazmat Fees May Apply)
Protein expressed in male leptotene and zygotene spermatocytes 264
MLZ-264
Background Information
LYAR, also known as Ly1 antibody reactive clone, has been found to regulate the intracellular strength that is stimulated by both T and B cell antigen receptors. It is essential for immune tolerance and certain changes to its function could stimulate the development of autoreactivity. LYAR is important in the immunological synapse and functions to inhibit the T cell response. LYAR is highly expressed in indifferentiated embryonic stem cells and may be important in maintaining the stem cell identity.
Product Information
Format
Affinity Purified
Control
Mouse embryonic stem cell lysate
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-LYAR Antibody (Ly1 reactive clone) detects level of LYAR (Ly1 antibody reactive clone) & has been published & validated for use in WB.
Key Applications
Western Blotting
Biological Information
Immunogen
GST-tagged recombinant protein corresponding to mouse LYAR.
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Species Reactivity
Mouse
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_079557
Gene Symbol
Lyar
LYAR
Purification Method
Affinity Purfied
UniProt Number
Q08288
UniProt Summary
SUBCELLULAR LOCATION: Nucleus › nucleolus
TISSUE SPECIFICITY: Very high levels in immature spermatocytes in testis. Expressed in ovary.
DEVELOPMENTAL STAGE: Expressed in testis and ovary at E15.5.
Evaluated by Western Blot in mouse embryonic stem cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected LYAR in 10 µg of mouse embryonic stem cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
