Miltenyi Biotec Peptivator Sars-Cov-2 Prot_S, Research Grade; For stimulation of 1×10E9 cells

Miltenyi Biotec PepTivator SARS-CoV-2 Prot_S is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the immunodominant sequence domains of the surface (or spike) glycoprotein (“S”) of SARS-Coronavirus 2 (GenBank MN908947.3, Protein QHD43416.1). The PepTivator SARS-CoV-2 Prot_S contains the sequence domains aa 304-338, 421-475, 492-519, 683-707, 741-770, 785-802, and 885 – 1273 (sequence end). | In contrast, PepTivator SARS-CoV-2 Prot_S Complete covers all functional domains (aa 5–1273), Prot_S1 the complete N-terminal S1 domain (aa 1–692) and Prot_S+ parts of the C-terminal S2 domain (aa 689–895). The complete S2 domain (and parts of the S1 domain: aa 304–338, 421–475, and 492–519) is covered, when PepTivator SARS-CoV-2 Prot_S and Prot_S+ are combined. | In vitro stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells. | | - MLTY (Additional S&H or Hazmat Fees May Apply)