Miltenyi Biotec Peptivator Sars-Cov-2 Prot_S1, Research Grade; For Stimulation Of 1×10e8 Cells

Miltenyi Biotec PepTivator SARS-CoV-2 Prot_S1 is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the N-terminal S1 domain of the surface glycoprotein ("S") of SARS-Coronavirus 2 (GenBank MN908947.3, Protein QHD43416.1). The PepTivator SARS-CoV-2 Prot_S1 contains the aa sequence 1–692 of the surface glycoprotein, also termed "spike" protein. | In contrast, PepTivator SARS-CoV-2 Prot_S Complete covers all functional domains (aa 5–1273), Prot_S covers selected immunodominant sequence domains of the spike protein (aa 304–338, 421–475, 492–519, 683–707, 741–770, 785–802, and 885–1273) and Prot_S+ parts of the C-terminal S2 domain (aa 689–895). The complete S2 domain (and parts of the S1 domain: aa 304–338, 421–475, and 492–519) is covered, when PepTivator SARS-CoV-2 Prot_S and Prot_S+ are combined. | In vitro stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells. - MLTY (Additional S&H or Hazmat Fees May Apply)