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Sigma-Aldrich Phenolphthalein A.C.S. Rea
List Price $206.00 Your Price $206.00
Sigma-Aldrich Phenolphthalein A.C.S. Reagent - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-105945-500G
MFG.PART: 105945-500G
UNSPSC: 12171500
Manufacturer: Sigma-Aldrich
grade
ACS reagent
Quality Level
200
form
powder
technique(s)
titration: suitable
visual transition interval
8.0-10, colorless to red
mp
261-263 °C (lit.)
solubility
acetone: soluble
density
1.27 g/cm3 at 32 °C
λmax
374 nm (2nd)
552 nm
application(s)
diagnostic assay manufacturing
hematology
histology
Related Categories
Hematology Stains
General description
Phenolphthalein is an indicator for acid-base titration reactions.[1] It changes from colorless to violet-red between pH 8.3-9.8, it is red in extremely acidic solutions, and colorless in extremely alkaline solutions.[2]
It is present as a nonionic, lipophilic lactone in aqueous neutral solutions. It exists as a hydrophilic dianion in alkaline solutions.
It is present as a nonionic, lipophilic lactone in aqueous neutral solutions. It exists as a hydrophilic dianion in alkaline solutions.
Application
Phenolphthalein has been commonly used as an indicator in the fields of biology and medicine. Its applications include:
- the development of novel technique to monitor the vacuum freeze-drying process[3]
- the determination of the depth of carbonation in concrete[4]
- the utilization of liquid marbles to sense gaseous environmental components
- the estimation of total acidity in vinegar
- the assessment of sodium hydroxide penetration into potatoes following chemical peeling
- as a model organic compound in the evaluation of the capture efficiency of various cyclodextrin constructs such as nanofiber-CD
Biochem/physiol Actions
Phenolphthalein is colorless in acidic solutions and turns pink in basic solutions.
Principle
Phenolphthalein undergoes structural modification when there is a change in pH or in the structural state of water.[1] It is a nonionic, lipophilic colorless lactone in aqueous neutral solutions and a hydrophilic dianion in alkaline solutions.[2]
pictograms
GHS08,GHS07
signalword
Danger
hcodes
H315,H341,H350,H361f
pcodes
P202 - P264 - P280 - P302 + P352 - P308 + P313 - P332 + P313
Hazard Classifications
Carc. 1B - Muta. 2 - Repr. 2 - Skin Irrit. 2
wgk_germany
WGK 3
PPE
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
| SKU | SIAL-105945-500G |
|---|---|
| Supplier Part Number | 105945-500G |
| UM | EA |
| UNSPSC | 12171500 |
| Manufacturer | Sigma-Aldrich |
| Temperature | room temp |
| Refrigerated-Frozen | N |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| Hazardous | Y |
| CAS Number | 77-09-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |