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Millipore This Anti-Glut-1 Antibody, Ct, Alexa Fluor® 647 Conjugate Is Validated For Use In Immunocytochemistry For The Detection Of Glut-1. - Mill (Additional S&H or Hazmat Fees May Apply)
Solute carrier family 2, facilitated glucose transporter member 1
Glucose transporter type 1, erythrocyte/brain
GLUT-1
HepG2 glucose transporter
GLUT-1, CT, Alexa Fluor® 488 Conjugate
Background Information
Solute carrier family 2, facilitated glucose transporter member 1 (UniProt P11166; also known as Glucose transporter type 1 erythrocyte/brain, GLUT-1, HepG2 glucose transporter, Human T-cell leukemia virus I and II receptor, Receptor for HTLV-1 and HTLV-2) is encoded by the SLC2A1 (also known as DYT9, DYT17, DYT18, EIG12, GLUT, GLUT1, HTLVR, GLUT1DS, PED) gene (Gene ID 6513) in human. Glucose transporters (GLUT-1 to GLUT-7) constitute a family of integral membrane glycoproteins that facilitate cellular glucose uptake. In addition to mediateing glucose uptake in adult tissues, GLUT-1 is the predominant glucose transporter in embryonic and fetal tissues. Two forms of GLUT-1 are found in human frontal cortex, the 55 kDa form of GLUT1 regulates import of glucose from blood to brain across the endothelial cells of the blood-brain barrier (BBB), whereas the 45 kDa form of GLUT1 predominantly regulates nonvascular glial glucose uptake.
Product Information
Format
AlexaFluor®647
Presentation
Purified rabbit conjugate antibody in PBS with 15 mg/ml BSA and 0.1% sodium azide
Quality Level
MQ100
Applications
Application
This Anti-GLUT-1 Antibody, CT, Alexa Fluor® 647 Conjugate is validated for use in Immunocytochemistry for the detection of GLUT-1.
Key Applications
Immunocytochemistry
Application Notes
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected GLUT-1 in HeLa and NIH/3T3 cells. The unconjugated antibody (Cat. No. 07-1401) is shown to be suitable also for ELISA, Western blotting, immunocytochemistry, and immunohistochemistry applications.
Biological Information
Immunogen
Synthetic peptide corresponding amino acids with the C-terminus of human GLUT-1 coupled to KLH (C-ELFHPLGADSQV).
Epitope
C-terminus
Concentration
Please refer to lot specific datasheet.
Host
Rabbit
Specificity
This antibody recognizes GLUT-1.
Species Reactivity
Human
Mouse
Rat
Species Reactivity Note
Human, Mouse, Rat. Predicted to react with Bovine, Feline, Porcine, Equine, Monkey based on 100% sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NM_006516
Gene Symbol
SLC2A1
GLUT1
Purification Method
Affinity Purfied
UniProt Number
P11166
Molecular Weight
~54 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Immunocytochemistry in A431 cells.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected GLUT-1 in A431 cells.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
