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AG Scientific Thapsigargin, 5 mg
List Price $429.83 Your Price $429.83
AG Scientific Thapsigargin (5mg) is a sesquiterpene lactone, known to inhibit sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) - AG (Additional S&H or Hazmat Fees May Apply)
NETA PART: RPI-T-1014-5MG
MFG.PART: T-1014-5MG
UNSPSC: 12352200
Manufacturer: AG Scientific
AG Scientific Thapsigargin is a sesquiterpene lactone that is known to inhibit sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA). Through the inhibition of SERCA, thapsigargin promotes the release and eventual depletion of intracellular calcium reserves, leading in turn to calcium influx.
Thapsigargins ability to regulate calcium influx has been shown to affect several physiological functions. This lactone is known to induce apoptosis by disrupting the ordinary organization of cytoskeletal structures.
Thapsigargin has played a large role in recent cancer research. Thapsigargin has been shown to be a weak promoter of skin tumors in mice. Intriguingly, however, researchers have also discovered potential uses for it in cancer treatment due to its ability to induce apoptosis. Using specific peptides, thapsigargin can be targeted to individual tumor sites. Studies have also been conducted into thapsigargins ability to sensitize tumors.
(Additional S&H Or Hazmat Fees May Apply) - AG
Thapsigargins ability to regulate calcium influx has been shown to affect several physiological functions. This lactone is known to induce apoptosis by disrupting the ordinary organization of cytoskeletal structures.
Thapsigargin has played a large role in recent cancer research. Thapsigargin has been shown to be a weak promoter of skin tumors in mice. Intriguingly, however, researchers have also discovered potential uses for it in cancer treatment due to its ability to induce apoptosis. Using specific peptides, thapsigargin can be targeted to individual tumor sites. Studies have also been conducted into thapsigargins ability to sensitize tumors.
(Additional S&H Or Hazmat Fees May Apply) - AG
| SKU | RPI-T-1014-5MG |
|---|---|
| Supplier Part Number | T-1014-5MG |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | AG Scientific |
| MSDS URL | Click here |
| Temperature | -20°C |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Israel |
| ProductLine | AG |
| Qty | 1 |
| MinOrderQty | 1 |
| Width | 8 |
| Depth | 8 |
| Height | 8 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 67526-95-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |