Cell Signaling Epcam (D9s3p) Rabbit mAb (Ihc Preferred)

Name: Cell Signaling Epcam (D9s3p) Rabbit mAb (Ihc Preferred)
SKU: CSIG-14452S
Price: 360.57 USD

List Price $360.57 Your Price $360.57

Cell Signaling Epcam (D9s3p) Rabbit mAb (Ihc Preferred) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-14452S

MFG.PART: 14452S

UNSPSC: 41116113

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	40
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunohistochemistry (Paraffin): 1:200, Flow Cytometry (Fixed/Permeabilized): 1:400}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. For a carrier-free (BSA and azide free) version of this product see product #55725.
Specificity/Sensitivity	EpCAM (D9S3P) Rabbit mAb recognizes endogenous levels of total EpCAM protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein specific to human EpCAM protein.
Background	Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+-independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). Research studies identified EpCAM as one of the first tumor-associated antigens, and it has long been a marker of epithelial and tumor tissue. Investigators have shown that EpCAM is highly expressed in cancer cells (reviewed in 2,3).

Specifications