ChemImpex Bexarotene; 96% (HPLC); 153559-49-0; MFCD00932428

Name: ChemImpex Bexarotene; 96% (HPLC); 153559-49-0; MFCD00932428
SKU: CMX-37674-100MG
Price: 215.04 USD

List Price $215.04 Your Price $215.04

ChemImpex Bexarotene; 96% (HPLC); 153559-49-0; MFCD00932428 - CMX (Additional S&H or Hazmat Fees May Apply)

NETA PART: CMX-37674-100MG

MFG.PART: 37674-100MG

UNSPSC: 12350000

Manufacturer: Chem Impex International

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Description

Bexarotene is a synthetic retinoid that has garnered attention for its potential applications in oncology and dermatology. This compound is primarily recognized for its role in the treatment of cutaneous T-cell lymphoma (CTCL), where it acts by modulating gene expression and promoting differentiation of malignant cells. Researchers have also explored its efficacy in various cancer types due to its ability to activate retinoid receptors, which can lead to tumor regression. Additionally, Bexarotene has shown promise in neurodegenerative disease research, particularly in Alzheimers disease, where it may help in reducing amyloid plaque formation.

The unique structure of Bexarotene allows for selective targeting of retinoid receptors, providing a distinct advantage over traditional retinoids. This specificity may result in fewer side effects and enhanced therapeutic outcomes, making it a valuable option for both clinical and research applications. Its versatility in addressing complex diseases highlights its significance in the pharmaceutical landscape, appealing to researchers and healthcare professionals seeking innovative solutions.

Specifications

Synonyms	Targretin
CAS Number	153559-49-0
Purity	≥ 96% (HPLC)
Molecular Formula	C₂₄H₂₈O₂
Molecular Weight	348.49
MDL Number	MFCD00932428
PubChem ID	82146
Melting Point	220 - 225 °C
Appearance	White to orange to green powder to crystal
Conditions	Store at < -20 °C

Safety & Regulations

Hazmat	No
Antibiotic	No
DEA-regulated	No
Warnings	-

Bexarotene is widely utilized in research focused on:

Cancer Treatment: Bexarotene is primarily used in oncology, particularly for treating cutaneous T-cell lymphoma (CTCL). Its ability to induce apoptosis in cancer cells makes it a valuable option for patients who have not responded to other therapies.
Neurodegenerative Disease Research: Researchers are exploring Bexarotenes potential in treating Alzheimers disease. Studies suggest it may help clear amyloid plaques in the brain, offering hope for new therapeutic strategies.
Skin Care Products: The compound is being investigated for its use in dermatological formulations. Its retinoid-like properties can improve skin texture and reduce signs of aging, making it appealing for cosmetic applications.
Pharmaceutical Development: Bexarotene serves as a model compound in drug discovery, helping scientists understand the mechanisms of retinoid action and developing new retinoid-based therapies.
Environmental Research: Its effects on wildlife and ecosystems are being studied, particularly in relation to its potential impact on endocrine systems, which can inform regulatory policies and environmental safety assessments.

Specifications

More Information
SKU	CMX-37674-100MG
Supplier Part Number	37674-100MG
UM	EA
UNSPSC	12350000
Manufacturer	Chem Impex International
Temperature	Store at < -20 °C
ProductLine	CMX
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	5
Hazardous	N
CAS Number	153559-49-0
Energy Star	No
Green	No
Controlled	N

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ChemImpex Bexarotene; 96% (HPLC); 153559-49-0; MFCD00932428

Specifications

Safety & Regulations

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