ChemImpex Nisoldipine; 98% (HPLC); 63675-72-9; MFCD00478055, 5G

Name: ChemImpex Nisoldipine; 98% (HPLC); 63675-72-9; MFCD00478055, 5G
SKU: CMX-38101-5G
Price: 591.37 USD

List Price $591.37 Your Price $591.37

ChemImpex Nisoldipine; 98% (HPLC); 63675-72-9; MFCD00478055 - CMX (Additional S&H or Hazmat Fees May Apply)

NETA PART: CMX-38101-5G

MFG.PART: 38101-5G

UNSPSC: 12350000

Manufacturer: Chem Impex International

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Description

Nisoldipine is a potent calcium channel blocker primarily used in the management of hypertension and angina pectoris. This compound works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Its unique structure, characterized by a 2-nitrophenyl group and multiple methyl substitutions, enhances its efficacy and selectivity, making it a preferred choice for patients who require effective blood pressure control with minimal side effects.

In addition to its cardiovascular applications, Nisoldipine has shown promise in research settings, particularly in studies exploring its effects on various vascular conditions. Its ability to selectively target calcium channels can be beneficial in developing treatments for other diseases where calcium regulation is crucial. Researchers and healthcare professionals appreciate Nisoldipine for its consistent performance and favorable pharmacokinetic profile, which allows for once-daily dosing, improving patient compliance.

Specifications

Synonyms	1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid Isobutyl methyl ester, Isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate
CAS Number	63675-72-9
Purity	≥ 99.5% (Assay, on dry basis)
Molecular Formula	C₂₀H₂₄N₂O₆
Molecular Weight	388.42
MDL Number	MFCD00478055
PubChem ID	4499
Melting Point	148 - 152 °C
Appearance	Yellow crystalline powder
Conditions	Store at 2 - 8 °C

Safety & Regulations

Hazmat	No
Antibiotic	No
DEA-regulated	No
Warnings	-

Nisoldipine is widely utilized in research focused on:

Cardiovascular Health: This compound is primarily used as an antihypertensive agent, helping to lower blood pressure in patients with hypertension. It relaxes blood vessels, improving blood flow and reducing the risk of heart-related issues.
Pharmaceutical Development: Researchers are exploring its potential in developing new medications for cardiovascular diseases. Its unique properties make it a candidate for formulations aimed at improving patient compliance and efficacy.
Clinical Trials: Nisoldipine is often involved in clinical studies to assess its effectiveness and safety in various populations, providing valuable data that can influence treatment guidelines.
Combination Therapies: It is frequently studied in combination with other antihypertensive drugs to enhance therapeutic outcomes, allowing for lower doses and reduced side effects compared to monotherapy.
Research on Drug Delivery Systems: The compound is being investigated for its role in novel drug delivery methods, which can improve the bioavailability and targeted action of cardiovascular medications.

Specifications

More Information
SKU	CMX-38101-5G
Supplier Part Number	38101-5G
UM	EA
UNSPSC	12350000
Manufacturer	Chem Impex International
Temperature	Store at 2 - 8 °C
ProductLine	CMX
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	5
Hazardous	N
CAS Number	63675-72-9
Energy Star	No
Green	No
Controlled	N

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ChemImpex Nisoldipine; 98% (HPLC); 63675-72-9; MFCD00478055, 5G

Specifications

Safety & Regulations

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