ChemImpex (R)-(-)-Rolipram; 98% (Chiral HPLC, HPLC); 85416-75-7; MFCD03093861, 10MG

Name: ChemImpex (R)-(-)-Rolipram; 98% (Chiral HPLC, HPLC); 85416-75-7; MFCD03093861, 10MG
SKU: CMX-38235-10MG
Price: 255.72 USD

List Price $255.72 Your Price $255.72

ChemImpex (R)-(-)-Rolipram; 98% (Chiral HPLC, HPLC); 85416-75-7; MFCD03093861 - CMX (Additional S&H or Hazmat Fees May Apply)

NETA PART: CMX-38235-10MG

MFG.PART: 38235-10MG

UNSPSC: 12350000

Manufacturer: Chem Impex International

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Description

(R)-(-)-Rolipram is a selective phosphodiesterase-4 (PDE4) inhibitor, recognized for its potential therapeutic applications in treating various inflammatory and neurodegenerative conditions. This compound has garnered attention in research for its ability to enhance cognitive function and reduce inflammation, making it a valuable candidate in the development of treatments for diseases such as Alzheimers and multiple sclerosis. Its unique structure allows for targeted action, minimizing side effects typically associated with broader-spectrum PDE inhibitors.

In addition to its pharmaceutical relevance, (R)-(-)-Rolipram is utilized in preclinical studies to explore its effects on memory enhancement and mood regulation. Researchers appreciate its specificity, which can lead to more effective therapies with fewer adverse reactions. The compounds ability to modulate cyclic AMP levels positions it as a promising agent in both academic and clinical settings, paving the way for innovative approaches in neuropharmacology and beyond.

Specifications

Synonyms	(R)-(-)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
CAS Number	85416-75-7
Purity	≥ 98% (Chiral HPLC, HPLC)
Molecular Formula	C₁₆H₂₁NO₃
Molecular Weight	275.35
MDL Number	MFCD03093861
PubChem ID	5092
Melting Point	132 - 136 °C
Appearance	White to almost white powder to crystal
Optical Rotation	[a]_D²⁰ = -29 to -34 ° (C=0.5 in Methanol)
Conditions	Store at < 0 °C

Safety & Regulations

Hazmat	No
Antibiotic	No
DEA-regulated	No
Warnings	-

(R)-(-)-Rolipram is widely utilized in research focused on

Neurological Disorders: This compound is being studied for its potential in treating conditions like depression and anxiety by inhibiting phosphodiesterase-4 (PDE4), which can enhance mood and cognitive function.
Anti-inflammatory Applications: Researchers are exploring its use in reducing inflammation, particularly in diseases such as asthma and chronic obstructive pulmonary disease (COPD), where PDE4 inhibition can lead to decreased airway inflammation.
Memory Enhancement: Studies suggest that (R)-(-)-Rolipram may improve memory and learning processes, making it a candidate for research in age-related cognitive decline and neurodegenerative diseases like Alzheimers.
Potential Cancer Research: There is ongoing investigation into its role in cancer therapy, particularly in enhancing the efficacy of certain chemotherapeutic agents by modulating the immune response.
Pharmaceutical Development: The compound serves as a valuable tool in drug formulation studies, particularly in optimizing formulations aimed at targeting specific neurological pathways.

Specifications

More Information
SKU	CMX-38235-10MG
Supplier Part Number	38235-10MG
UM	EA
UNSPSC	12350000
Manufacturer	Chem Impex International
Temperature	Store at < 0 °C
ProductLine	CMX
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	5
Hazardous	N
CAS Number	85416-75-7
Energy Star	No
Green	No
Controlled	N

Provide Content Correction

NETA PART NO.	Quantity

ChemImpex (R)-(-)-Rolipram; 98% (Chiral HPLC, HPLC); 85416-75-7; MFCD03093861, 10MG

Specifications

Safety & Regulations

Product Title