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Millipore Anti-Dmrt2 Antibody Is An Antibody Against Dmrt2 For Use In Western Blotting And Immunohistochemistry. - Mill (Additional S&H or Hazmat Fees May Apply)
Doublesex- and mab-3-related transcription factor 2
Doublesex-like 2 protein
Background Information
Doublesex- and mab-3-related transcription factor 2 is encoded by the DMRT2 gene in human and directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to its early epaxial enhancer element. In addition, it is also involved in somite develoment during embryogenesis. The human protein shares a DM DNA-binding domain with Drosophila doublesex (dsx) and C. elegans mab3 gene products involved in sex determination.
Product Information
Format
Affinity Purified
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-DMRT2 Antibody is an antibody against DMRT2 for use in Western Blotting and Immunohistochemistry.
Key Applications
Western Blotting
Immunohistochemistry
Application Notes
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected DMRT2 in human kidney and rat testis tissue.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human DMRT2.
Concentration
Please refer to lot specific datasheet.
Host
Rabbit
Species Reactivity
Human
Rat
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_870987
Gene Symbol
DMRT2
DSXL2
Purification Method
Affinity Purfied
UniProt Number
Q9Y5R5
Molecular Weight
~70 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in human kidney tissue lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected DMRT2 in 10 µg of human kidney tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
