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Millipore Anti-Phospho Psd95 Antibody (Thr19) Is An Antibody Against Phospho Psd95 (Thr19) For Use In Western Blotting, Peptide Inhibition Assay, Immunohistochemistry (Paraffin). - Mill (Additional S&H or Hazmat Fees May Apply)
PSD95 (postsynaptic density95) represent a class of anchoring proteins which serve to localize various neuronal ion channels to post-synaptic densities. PSD95 and related proteins contain PDZ domains, which interact with NMDA receptors and voltage-gated K+ channels via a ET/SXV motif in the cytoplasmic carboxyl terminus of the receptor channels.
Product Information
Format
Affinity Purified
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-phospho PSD95 Antibody (Thr19) is an antibody against phospho PSD95 (Thr19) for use in Western Blotting, Peptide Inhibition Assay, Immunohistochemistry (Paraffin).
Key Applications
Western Blotting
Peptide Inhibition Assay
Immunohistochemistry (Paraffin)
Application Notes
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected phospho PSD95 (Thr19) in human cerebellum, human cerebral cortex, and human thalamus tissue.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human phospho PSD95 (Thr19) near the N-Terminus.
Epitope
Near N-Terminus
Concentration
Please refer to lot specific datasheet.
Host
Rabbit
Species Reactivity
Human
Species Reactivity Note
Human. Predicted to react with Mouse, Rat, Bovine based on 100% sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_001122299
Gene Symbol
DLG4
PSD95
Modifications
Phosphorylation
Purification Method
Affinity
UniProt Number
P78352
Molecular Weight
~80 kDa observed. The calculated molecular weight is 80 kDa, however phospho PSD95 (Thr19) has been shown as a ~80-95 kDa band in some western blots (Nelson, C.D., et al. (2013). J. of Neuroscience. 33(29):12122-12135).
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in human fetal brain tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected phospho PSD95 (Thr19) in 10 µg of human fetal brain tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
