Sigma-Aldrich Aniracetam - Cas 72432-10

Assay

≥99% (HPLC)

Quality Level

100

Form

solid

Manufacturer/Tradename

Calbiochem^®

Storage Condition

OK to freeze
protect from light

Color

white

Solubility

DMSO: 100 mm

Storage Temp.

2-8°C

Inchi

1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,2-3,8H2,1H3

Inchi Key

ZXNRTKGTQJPIJK-UHFFFAOYSA-N

General Description

A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).A positive allosteric modulator selective for AMPA receptors. Slows down AMPA receptor deactivation rate without altering the agonist potency. A leading candidate of ampakine nootropic for cognitive enhancement. Widely used in studies in a variety of brain functions (i.e. learn and memory, cognition) and disorders (depression, anxiety disorder, Alzheimer′s disease, and aging).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

Biochem/Physiol Actions

Primary Target
AMPA receptors

Warning

Toxicity: Standard Handling (A)

Other Notes

Koliaki, C., et Al. 2012.CNS Neuroscience & Therapeutics. 18,302.
Lynch, g., et Al. 2011.Pharmacol. Biochem. Behav. 99,116.
Nakamura, K., et Al. 2001.Eur. J. Pharmacol. 420,33.
Ito, I. et Al., 1990.J. Physiol. 424,553.
Isaacson et Al., 1991.PNAS. 88,1093.CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany