Sigma-Aldrich Manganese(IV) Oxide (Preci

Quality Level

200

Form

powder

Potency

>3478 mg/kg LD₅₀, oral (Rat)

Reaction Suitability

reagent type: oxidant

Solubility

insoluble <0.001 g/L

Density

5.21 g/cm³at 21 °C

Bulk Density

600‑800 kg/M³

Storage Temp.

2-30°C

Inchi

1S/Mn.2O

Inchi Key

NUJOXMJBOLGQSY-UHFFFAOYSA-N

Related Categories

Oxidation Reagents

Application

Manganese(IV) oxide (MnO₂) can be used as an oxidizing agent for the oxidation of:

• Allylic alcohols to α, β-ethylenic aldehydes, or ketones.
• Propargylic alcohols to alkynic aldehydes or ketones.
• Benzylic and heterocyclic alcohols to conjugated aromatic aldehydes or ketones.
• Amines to aldehydes, imines, amides, and diazo compounds.Methyl arenes to form primary amides in the presence of urea and oxygen.
• MnO₂can also be used to synthesize disubstituted oxazolines from aldoximes via in situ nitrile oxide formation. Non-activated cyclic and acyclic alcohols oxidized to ketone analogs using stoichiometric MnO₂and a ruthenium catalyst.

Analysis Note

Assay (iodometric, calc. on dried substance): ≥ 90.0 %
Loss on drying: ≤ 3.5 %
Oxidation Activity: passes test

Pictograms

GHS07,GHS08

Signalword

Warning

Hcodes

H302 + H332 - H373

Pcodes

P260 - P264 - P270 - P301 + P312 - P304 + P340 + P312 - P314

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 2 Inhalation

Target_Organs

Brain

Storage Class

13 - Non Combustible Solids

Wgk_Germany

WGK 1

Flash_Point_F

does not flash

Flash_Point_C

does not flash