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Miltenyi Biotec Cd94-Apc; 0.5 mL
List Price
$506.00
Your Price
$506.00
Miltenyi Biotec Cd94-Apc - MLTY (Additional S&H or Hazmat Fees May Apply)
NETA PART:
MLTY-170-081-033
MFG.PART:
170-081-033
UNSPSC:
41116015
Manufacturer:
Miltenyi Biotec
Miltenyi Biotec REA113 recognizes CD94, an approximately 45 kDa, single pass, type II transmembrane protein, which belongs to C-type lectin superfamily. CD94 associates covalently with NKG2 family members and forms disulfide-bonded heterodimers. CD94-NKG2 receptors bind HLA-E, the non-classical MHC class Ib molecule. Depending on the associated NKG2 member, CD94-NKG2 heterodimer transmits either activating or inhibitory signal. For example, via immunoreceptor tyrosine–based inhibitory motifs (ITIMs) containing NKG2A, CD94-NKG2A heterodimers inhibit NK cell cytotoxicity. Besides NK cells, expression of CD94-NKG2 heterodimers is also shown on NK-T cells and a small percentage of CD8 cells in mice, where the crosslinking of CD94-NKG2 was shown to reduce the level of spontaneous apoptosis. Additional Information: Clone REA113 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)
| SKU | MLTY-170-081-033 |
|---|---|
| Featured | No |
| Supplier Part Number | 170-081-033 |
| UM | EA |
| UNSPSC | 41116015 |
| Manufacturer | Miltenyi Biotec |
| MSDS URL | Click here |
| ProductLine | MLTY |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| ACT Ecolabel | No |