Revvity Pd-1 (Human) Lance Ultra Tr-Fret Detection Kit

Revvity The Lance® Ultra Human Pd-1 Detection Kit Is Designed For Detection And Quantitation Of Human Pd-1 In Buffered Solution And Cell Culture Media Using A Homogeneous Tr-Fret (No-Wash Steps, No Separation Steps) Assay. No-Wash Steps, No Separation Steps Tr-Fret Technology Sensitive Detection High Reproducibility Faster Time-To-Results Easy Automation 96-Well, 384-Well, And 1536-Well Formats Lance® And Lance® (Lanthanide Chelate Excite) Ultra Are Our Tr-Fret (Time-Resolved Fluorescence Resonance Energy Transfer), Homogeneous (No Wash) Technologies. One Antibody Of Interest Is Labeled With A Donor Fluorophore (A Lance Europium Chelate) And The Second Molecule Is Labeled With An Acceptor Fluorophore (Ulight™ Dye). Upon Excitation At 320 Or 340 Nm, Energy Can Be Transferred From The Donor Europium Chelate To The Acceptor Fluorophore If Sufficiently Close For Fret (~10 Nm). This Results In The Emission Of Light At 665 Nm. Programmed Cell Death Protein 1 (Pd-1), Also Known As Cluster Of Differentiation 279 (Cd279), Belongs To Immunoglobulin Superfamily And Is A Transmembrane Receptor Protein. Pd-1 Is Present On T -Cells Or B-Cells And Binds To Ligands, Such As Pd-L1 And Pd-L2, To Down Regulate The Immune System By Modulating Many Other Cytokines And Cytokine Receptors. Anti Pd-1 Antibody Drugs Been Shown To Enhance The Immune Systems Of Several Types Of Cancer Patients.S - PEGSK (Additional S&H Or Hazmat Fees May Apply)