Revvity Fluorescent Imaging Agent Panel - Vascular

Revvity Vascular injury can have numerous causes, including peripheral vascular disease, thrombosis, aneurysm, atherosclerosis, and drug induced vascular injury. Vascular injury may progress into changes in vascular integrity, remodeling, inflammation, and fibrosis. This panel of fluorescent imaging probes detects cellular and molecular players in vascular pathology, allowing the ability to non-invasively characterize biological changes associated with disease progression or treatment efficacy. The availability of probes at 680 nm and 750 nm wavelengths further offer the opportunity for multiplex imaging of appropriate probe combinations to maximize information gained from research animals. The Vascular In Vivo Fluorescent Agents Panel includes the following five probes: Part Number Fluorescent Probe Biological Target NEV10054EX AngioSense 680 EX Vascular probe: Provides vascular contrast or vascular leak imaging NEV10168 MMPSense 750 FAST Pan-MMP activatable probe: Secreted protease involved in vascular remodeling and angiogenesis Secreted by vascular inflammatory cells NEV10645 IntegriSense 680 V3 integrin targeted probe: Marker on neovasculature and inflammatory cells involved in vascular inflammation NEV11112 Cat B 680 FAST Cathepsin B activatable probe: Lysosomal marker of cells in vascular inflammation NEV11171 ProSense 750 FAST Pan-cathepsin activatable probe: Lysosomal marker of inflammatory cells in vascular inflammation - PEMSD (Additional S&H or Hazmat Fees May Apply)