GenScript Toxineraser™ Endotoxin Removal Kit; 1Kit

Name: GenScript Toxineraser™ Endotoxin Removal Kit; 1Kit
SKU: GSCRPT-L00338
Price: 126.00 USD

List Price $126.00 Your Price $126.00

GenScript Toxineraser™ Endotoxin Removal Kit - GSCRPT (Additional S&H or Hazmat Fees May Apply)

NETA PART: GSCRPT-L00338

MFG.PART: L00338

UNSPSC: 41105322

Manufacturer: GenScript USA Inc

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Description

Overview

Product Description

Lipopolysaccharide (LPS) is a bacterialendotoxin, and a major constituent of the cell walls of gram- negativebacteria. During gram-negative bacteremia or endotoxemia, LPS is the principalpathophysiological mediator by which bacteria can cause hypotension, organfailure, disseminated intravascular coagulation, and fatal shock in mammalianhosts. Removal of endotoxin from drugs, injectables, and other biologicalproducts is necessary but can also be very difficult.
GenScript’s ToxinEraser™is an endototoxin removal resin of high efficiency. It is based on affinitymatrix of modified polymyxin B (PMB), which allows highly efficient endotoxinremoval. The final endotoxin level can be decreased to less than 0.1 EU/ml withrepeated use of ToxinEraser™ endotoxin removalresin. Final removal efficiency may vary depending on the sample type/source.

Key Features

High stability and highremoval efficiency
High binding capacity: >2, 000, 000 EU / ml (CV)
Fast flow without anyconstant speed pump
Reusable up to five timesif properly regenerated
Ready-to-use reagents andmaterials, such as equilibration buffer, collection tubes, etc.

Product Introduction

Kit Contents

Kit Contents （Cat. No.:L00338）	PK
ToxinEraser™ Endotoxin Removal Resin	1.5 ml pre-packed column
Regeneration Buffer	125 ml
Equilibration Buffer	125 ml
Flow-Speed Control	1
Collection Tubes	1 bag (3 Tubes)
Tips (1 mL)	2 bags (6 Tips/bag)
Protocol	1

Product Information

Characteristics of ToxinEraser™EndotoxinRemoval Resin

Size	1.5 ml in pre-packedcolumn
Binding Capacity	Up to 2,000,000 EU/mlresin
Ligand	Modified PMB(Polymixin B)
pH Stability	pH 5 -10
Support Matrix	4% cross-linkedagarose, spherical beads
Mean Particle Size	90 μm
Storage	2°C to 8°C (Do notfreeze.)
Equilibration Buffer	Phosphate-Buffer, pH8.0
Regeneration Buffer	Sodium Phosphate-Buffer, pH8.0; Triton-114
Types of substancesthat can be applied to the column	Purified recombinant proteins,peptides, antibodies, polysaccharides, etc.
Tolerable Ionic Strength	0.1 to 0.5 M NaCl
Tested reagents that do notinterfere with performance	20% DMSO, 20% ethanol, 20%glycerol;1 M urea, 300 mM imidazole; 0.05% Tween 20, 10 mM DTT.

Storage

Regeneration and storage of the Column.
To regenerate the column, wash the column with 10 mlof equilibration buffer and allow the column to drain completely. Add ethanolto the regeneration buffer to a final concentration of 20%, adding at least 1.5ml to the column for storage. Store at 2-8°C. Do not freeze.

For research andmanufacturing use. Direct human use, including taking orally and injection are forbidden.

Specifications

More Information
SKU	GSCRPT-L00338
Supplier Part Number	L00338
UM	EA
UNSPSC	41105322
Manufacturer	GenScript USA Inc
Temperature	Regeneration and storage of the Column. To regenerate the column, wash the column with 10 mlof equilibration buffer and allow the column to drain completely. Add ethanolto the regeneration buffer to a final concentration of 20%, adding at least 1.5ml to t
ProductLine	GSCRPT
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	7
Hazardous	N
Energy Star	No
Green	No
Controlled	N

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NETA PART NO.	Quantity

GenScript Toxineraser™ Endotoxin Removal Kit; 1Kit

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