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GenScript Cho-K1/Mt1/Gα15 Stable Cell Line; 2vials
List Price
$8,925.00
Your Price
$8,925.00
GenScript Cho-K1/Mt1/Gα15 Stable Cell Line - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART:
GSCRPT-M00424
MFG.PART:
M00424
UNSPSC:
41105322
Manufacturer:
GenScript USA Inc
Description
Melatonin binds to two specific G-protein coupled receptors (GPCR), MT1 (MTNR1A/MEL1A) and MT2 (MTNR1B/MEL1B). MT1 receptors signal via inhibitory G proteins (Gαi and Gαo) leading to adenylate cyclase inhibition and possibly inositol phosphate stimulation in recombinant systems. In certain native tissues (e.g. sheep pars tuberalis, rat cerebral and caudal arteries) melatonin responses are presumably mediated through activation of MT1 receptors. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. |
Synonyms
MT1 receptor, ML1A, MEL1A, ML1A, Mel1a, MEL-1A-R, mel1a melatonin receptor, mel1a receptor, melatonin receptor 1A, melatonin receptor type 1A, MelR
Overview
| Applications | Functional assay for MT1 receptor |
Product Introduction
| Storage | Liquid nitrogen immediately upon delivery |
| Species | Human |
Culture Conditions
| Freeze Medium | 45% culture medium, 45% FBS (Cat. #10099-141, Gibco), 10% DMSO (Cat. #D2650, Sigma) |
| Culture Medium | Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin (Cat. #R250-01, Life Technologies), 100 μg/ml Hygromycin B (Cat. #10687010, Invitrogen) |
| SKU | GSCRPT-M00424 |
|---|---|
| Featured | No |
| Supplier Part Number | M00424 |
| UM | EA |
| UNSPSC | 41105322 |
| Manufacturer | GenScript USA Inc |
| Temperature | Liquid nitrogen immediately upon delivery |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |