Corning Life Sciences

The Falcon 96 Multiwell Insert System is a cell culture insert platform suitable for both manual and robotic screening of compounds in cell-based assays. The system has been tested for its ability to produce a differentiated monolayer of Caco-2, LLC-PK1, and MDCK cells making it an ideal platform for in vitro bioavailability and permeability studies.

This automation compatible platform is composed of a 1.0 µm pore size PET membrane-based 96 Multiwell Insert plate, a media feeder tray, and a lid. The drop-in baffle for the Feeder Tray mitigates media sloshing and lowers the risk of contamination. To analyze individual samples, simply transfer the insert plate into the Falcon 96 Square Well, Angled-Bottom Plate. If desired, the Falcon 96 Square Well, Angled-Bottom Plate may be used in conjunction with the insert for culturing the cells, eliminating the transfer step from the single-well feeder tray for sample analysis.

• Automation compatible design
• Format compatible with most robots and fluid handling instruments
• Complete sample recovery
• The Falcon 96 Square Well, Angled-Bottom Plate features an angled bottom for more complete sample utilization
• Excellent reproducibility
• One-piece feeder tray enhances consistency in well-to-well monolayer growth
• Total assay flexibility—ideal for transport studies
• System can be used with many cell lines including Caco-2, MDCK, and LLC-PK1, for basal to apical or apical to basal measurements of drug transport