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GenScript Anti-Teclistamab Antibody (10h1), Mab, Mouse; 40 μg
List Price $144.00 Your Price $144.00
GenScript Anti-Teclistamab Antibody (10h1), Mab, Mouse - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-A02253-40
MFG.PART: A02253-40
UNSPSC: 12352203
Manufacturer: GenScript USA Inc
Overview
| Specificity | This product is specific for Teclistamab |
| Host Species | Mouse |
| Immunogen | Teclistamab |
| Conjugate | Unconjugated |
Applications
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||
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Properties
| Form | Lyophilized |
| Storage Buffer | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| Storage Instructions | The lyophilized product remains stable for up to 1 year at -20 °C from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| Purification | Protein A affinity column |
| Isotype | Mouse IgG1, κ |
| Clonality | Monoclonal |
| Clone ID | 10H1E1 |
| Note | GenScript can customize this product per customers request including product size, buffer components, etc. |
Background
| Target Background | Teclistamab, also known as Tecvayli, is a therapeutic monoclonal antibody specifically designed to address relapsed and refractory multiple myeloma. It is a bispecific antibody that effectively targets both the CD3 receptor found on T-cells and the B-cell maturation antigen (BCMA) expressed on malignant multiple myeloma B-lineage cells. Teclistamab is composed of two arms, one targeting BCMA and the other targeting CD3. These arms are connected by two interchain disulfide bonds, enabling the drug to engage CD3-expressing T cells and direct them towards BCMA-expressing cells. This mechanism facilitates T cell-mediated cytotoxicity to combat the targeted cells. |
| Synonyms | Teclistamab; teclistamab-cqyv; Tecvayli; TECVAYLI |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-A02253-40 |
|---|---|
| Supplier Part Number | A02253-40 |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | GenScript USA Inc |
| Temperature | The lyophilized product remains stable for up to 1 year at -20 °C from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |