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Millipore Anti-Kdr/Flk-1/Vegfr2 Antibody, Clone Ch-11 Detects Level Of Kdr/Flk-1/Vegfr2 & Has Been Published & Validated For Use In Elisa, Ic & Wb. - Mill (Additional S&H or Hazmat Fees May Apply)
Anti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11 detects level of KDR/Flk-1/VEGFR2 & has been published & validated for use in ELISA, IC & WB.
Key Applications
ELISA
Immunocytochemistry
Western Blotting
Biological Information
Immunogen
Recombinant protein corresponding to residues 1158-1345 of murine KDR/Flk-1
Clone
clone CH-11
Host
Mouse
Specificity
KDR/Flk-1
Isotype
IgG1
Species Reactivity
Human
Mouse
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NM_010612
Gene Symbol
KDR
VEGFR-2
VEGFR2
VEGFR
CD309
FLK1
Purification Method
Protein A chromatography
UniProt Number
P35968
UniProt Summary
FUNCTION: SwissProt: P35968 # Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. SIZE: 1356 amino acids; 151527 Da SUBUNIT: Interacts with SHB upon VEGF activation. Interacts with HIV-1 Tat. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SIMILARITY: SwissProt: P35968 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
Molecular Weight
230kDa
Product Usage Statements
Quality Assurance
routinely evaluated by immunoblot on RIPA lysates from HUVEC cells
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
