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PBS, 0.02% sodium azide before the addition of glycerol to 10%
Quality Level
MQ100
Applications
Application
Anti-CPI-17 Antibody is an antibody against CPI-17 for use in WB.
Key Applications
Western Blotting
Application Notes
NOT cross-reactive in yeast.
Biological Information
Immunogen
Recombinant protein, full length pig CPI-17
Host
Rabbit
Specificity
CPI-17
Isotype
IgG
Species Reactivity
Bovine
Human
Mouse
Pig
Rat
Rabbit
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NM_033256
Entrez Gene Summary
PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase (see MIM 603768). Inhibition leads to increased myosin phosphorylation and enhances smooth muscle contraction in the absence of increased intracellular Ca(2+) concentration.[supplied by OMIM]
Gene Symbol
PPP1R14A
CPI-17
PPP1INL
17-KDasprotein
CPI17
Purification Method
Protein A chromatography
UniProt Number
Q96A00
UniProt Summary
FUNCTION: SwissProt: Q96A00 # Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. SIZE: 147 amino acids; 16693 Da SUBCELLULAR LOCATION: Cytoplasm (By similarity). TISSUE SPECIFICITY: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. SIMILARITY: SwissProt: Q96A00 ## Belongs to the PP1 inhibitor family.
Molecular Weight
22kDa
Product Usage Statements
Quality Assurance
routinely evaluated by immunoblot on RIPA lysates from mouse brain nuclear fraction and pig carotid artery tissue extract
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
