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Anti-Fbx2 Antibody is an antibody against Fbx2 for use in WB.
Key Applications
Western Blotting
Application Notes
Western blot: 1:5,000-1:10,000 on mouse brain lysate.
Optimal working dilutions must be determined by end user.
Biological Information
Immunogen
Synthetic peptide
Host
Rabbit
Specificity
Fbx2. By Western blot the antibody recognizes a band at ~35 kDa on mouse brain lysate.
Species Reactivity
Mouse
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NM_012168.4
Entrez Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state.
Gene Symbol
FBXO2
Fbs1
FBG1
Fbg1
Nfb42
FBX2
NFB42
Purification Method
Serum
UniProt Number
Q9UK22
UniProt Summary
FUNCTION: SwissProt: Q9UK22 # Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. SIZE: 296 amino acids; 33328 Da SUBUNIT: Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity). SIMILARITY: SwissProt: Q9UK22 ## Contains 1 F-box domain. & Contains 1 FBA (F-box associated) domain.
Molecular Weight
35 kDa
Product Usage Statements
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
