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Millipore This Anti-Wnt-11 Antibody Is Validated For Use In Western Blotting For The Detection Of Wnt-11. - Mill (Additional S&H or Hazmat Fees May Apply)
Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. Transcription of Wnt family genes appears to be developmentally regulated in a precise temporal and spatial manner. Wnt-11 activity is required for cells to undergo correct convergent extension movements during gastrulation. Wnt-11 is also expressed in the lung mesenchyme, the urorectal septum, the urogenital folds, the labioscrotal swellings, and the cortex of the adrenal gland. Unlike other Wnt family members, Wnt-11 is not expressed in the neuroepithelium of the central nervous system. Wnt-11, along with Wnt-8c, is expressed in the posterior region of the chick embryo in the caudal paraxial mesoderm that underlies the prospective caudal neural plate.
Product Information
Format
Affinity Purified
Presentation
Purified rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
This Anti-Wnt-11 Antibody is validated for use in Western Blotting for the detection of Wnt-11.
Key Applications
Western Blotting
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminus of Human Wnt-11.
Epitope
C-terminus
Concentration
Please refer to lot specific datasheet.
Host
Rabbit
Species Reactivity
Human
Species Reactivity Note
Human. Predicted to react with Mouse, Rat, Bovine, Rabbit based on 100% sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_004617
Gene Symbol
WNT11
Purification Method
Antigen Affinity Purified
UniProt Number
O96014
Molecular Weight
~39 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blot in human osteosarcoma U2OS cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected WNT-11 in 10 µg of human osteosarcoma U2OS cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
