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Millipore Anti-Zfp36l1 Detects Levels Of Zfp36l1 Proteins & Has Been Published & Validated For Use In Wb. - Mill (Additional S&H or Hazmat Fees May Apply)
As a member of the ZFP36/tristetraprolin (TTP) family of zinc finger proteins, ZFP36L1 serves as an RNA-binding protein (RBP) that is known to interact with AU-rich elements in the 3’-untranslated region of mRNAs, resulting in their degradation. It serves as a target for Keratinocyte-derived growth factors and cytokines. ZFP36L1 is reported to play an important role in various physiological processes, including wound healing, epidermal homeostasis, inflammation, erythroid differentiation, thymocyte development, and in the prevention of malignant transformation. Defects in the ZFPP36L1 gene have been implicated in Mutiple Sclerosis and cancer.
Product Information
Format
Affinity Purified
Control
HeLa cell lysate
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-ZFP36L1 detects levels of ZFP36L1 proteins & has been published & validated for use in WB.
Key Applications
Western Blotting
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminus of Human ZFP36L1.
Epitope
C-terminus
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody recognizes the C-terminus of ZFP36L1.
Species Reactivity
Human
Mouse
Rat
Bovine
Horse
Canine
Species Reactivity Note
Demonstrated to react with Human. Predicted to react with Mouse, Rat, Bovine, Horse, and Canine based on 100% sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_001231627
Gene Symbol
ZFP36L1
BERG36
BRF1
ERF1
RNF162B
TIS11B
Purification Method
Affinity Purfied
UniProt Number
Q07352
Molecular Weight
~38 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected ZFP36L1 in 10 µg of HeLa cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
