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Millipore Anti-Lefty Antibody, Clone 1g9.1 | Mabd146 Is An Antibody Against Lefty Antibody For Use In Western Blotting. - Mill (Additional S&H or Hazmat Fees May Apply)
Left-right determination factor 1 (LEFTY1) also known as Left-right determination factor B, Protein lefty-1, Protein lefty-B, and encoded by the gene name LEFTYB, LEFTY1, LEFTB, is a member of the the TGF-beta family. LEFTY1 collaborates with other members of the TGFβ (Transforming Growth Factor) family to establish a left-right axis that dictates the asymmetrical distribution of internal organs during vertebrate embryogenesis. Mice deficient in LEFTY1 are affected by pulmonary isomerism and abnormal placement of vascular tracts, possibly the result of unregulated expression of LEFTY2 and NODAL.
Product Information
Format
Purified
Presentation
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-Lefty Antibody, clone 1G9.1 | MABD146 is an antibody against Lefty Antibody for use in Western Blotting.
Key Applications
Western Blotting
Application Notes
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Lefty in 10 µg of C2C12 and NIH-3T3 cell lysate.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human Lefty and spans the pro and mature cleavage sites.
Clone
1G9.1
Concentration
Please refer to lot specific datasheet.
Host
Mouse
Isotype
IgMκ
Species Reactivity
Rat
Mouse
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_066277
Gene Symbol
LEFTY1
LEFTB
LEFTYB
UNQ278/PRO317
Purification Method
Purified by Ion-Exchange Chromatography
UniProt Number
O75610
Molecular Weight
~40 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in L6 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Lefty in 10 µg of L6 cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
