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GenScript Vegf165, Human; 1mg
List Price
$1,705.00
Your Price
$1,705.00
GenScript Vegf165, Human - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART:
GSCRPT-Z02689-1
MFG.PART:
Z02689-1
UNSPSC:
41105300
Manufacturer:
GenScript USA Inc
Product Introduction
| Species | Human | |
| Protein Construction |
| |
| Purity | > 95% as analyzed by SDS-PAGE | |
| Endotoxin Level | < 0.5 EU/μg of protein by gel clotting method | |
| Biological Activity | ED50 of 1.0-5.0 ng/ml, measured by the dose-dependent stimulation of the proliferation of HUVEC cells, corresponding to a specific activity of 2.0 × 105-1.0 × 106 units/mg. | |
| Expression System | P. pastoris | |
| Apparent Molecular Weight | ~ 38-40 kDa, on SDS-PAGE under non-reducing conditions ~ 18-20 kDa, on SDS-PAGE under reducing conditions Structure/form: Disulfide-linked homodimer | |
| Formulation | Lyophilized after extensive dialysis against 25 mM HEPES, 150 mM NaCl, pH 7.0. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | Vascular Endothelial Growth Factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, Vascular Endothelial Growth Factor (VEGF) plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates Vascular Endothelial Growth Factor (VEGF) in the induction of tumor metastasis and intra-ocular neovascular syndromes. Vascular Endothelial Growth Factor (VEGF) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. |
| Synonyms | VEGF-165; Vascular Endothelial Growth Factor 165; VPF; Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen; Vascular Permeability Factor |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z02689-1 |
|---|---|
| Featured | No |
| Supplier Part Number | Z02689-1 |
| UM | EA |
| UNSPSC | 41105300 |
| Manufacturer | GenScript USA Inc |
| Temperature | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (examp |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |