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Millipore Anti-ATP-Binding Cassette Antibody, Sub-Family B (Mdr/Tap)
Millipore Anti-ATP-Binding Cassette Antibody, Sub-Family B (Mdr/Tap)
List Price$510.60Your Price$510.60
Millipore Anti-ATP-Binding Cassette, Sub-Family B (Mdr/Tap), Member 1a Detects Levels Of ATP-Binding Cassette Proteins & Has Been Published & Validated For Use In Wb. - Mill (Additional S&H or Hazmat Fees May Apply)
Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A
Alternate Names
ATP binding cassette transporter 1
ATP-binding cassette 1
ATP-binding cassette transporter 1
ATP-binding cassette, sub-family A (ABC1), member 1
ATP-binding cassette, sub-family A member 1
ATP-binding cassette, sub-family A, member 1
Cholesterol efflux regulatory protein
Background Information
This protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. There are seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The MDR/TAP subfamily are involved in multidrug resistance. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes, and celiac disease.
Product Information
Format
Serum
Presentation
Raw rabbit serum with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A detects levels of ATP-binding cassette proteins & has been published & validated for use in WB.
Key Applications
Western Blotting
Application Notes
Western Blot Analysis: A 1:5000 dilution of this lot detected baculovirus expressed recombinant ABC protein.
Biological Information
Immunogen
Recombinant
Epitope
AA N629 – W704
Host
Rabbit
Species Reactivity
Mouse
Rat
Species Reactivity Note
Mouse. Expected to react with rat based on sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NM_011076
Entrez Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a p-glycoprotein which actively transports a variety of hydrophobic amphipathic drugs and plays a major role in the blood-brain barrier permeability of certain drugs. [provided by RefSeq]
Gene Symbol
ABC-1
ABC1
CERP
FLJ14958
HDLDT1
MGC164864
MGC165011
OTTHUMP00000021833
TGD
membrane-bound
Molecular Weight
141 kDa
Product Usage Statements
Quality Assurance
Routinely evaluated by Western Blot on baculovirus expressed recombinant ABC protein.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain at -20°C for up to 12 months from date of receipt.
