Revvity HTRF Hman Phoho-Cyclin B1 (Ser126) Detection Kit, 10,000 Aay Point

Revvity Thi HTRF cell-aed aay rovide a convenient and accrate way to detect hohorylated Cyclin B1 at Ser126. Cyclin B family memer (inclding Cyclin B1 and Cyclin B2) are imortant reglator of cell cycle rogreion. They are integral mediator of the growth factor-deendent tranition from G2 to Mitoi hae, laying the role of the reglatory nit of CDK1.Cyclin B1 i reglated in the reence of extracelllar mitogenic timli and i eqently raidly downreglated y roteaomal degradation following it hohorylation on Ser126.Cyclin B1 i often overexreed in many cancer. Sch anormal overexreion of Cyclin B1 relt in dyreglated CDK1 activity and can lead to tmorigenei.-PEGSK(Additional S&H Or Hazmat Fees May Apply)