Roche Diagnostics Corporation Cd2 (Mrq-11) Pab, Cell Marque

Roche Diagnostics Corporation cd2 (mrq-11) pab, cell marque; cd2 can be considered a pan-t cell antigen and is therefore useful for the identification of virtually all normal t lymphocytes. it is also very useful in the assessment of lymphoid malignancies as it is expressed in the majority of precursor and post-thymic lymphomas and leukemias and is not expressed by b neoplasms (foon & todd, 1986). as with other pan-t cell antigens, cd2 may be aberrantly deleted in some neoplastic t cell population, especially peripheral t cell lymphomas. rarely slg+ b cell neoplasms have been described to form spontaneous e-rosettes but these reactions are not mediated via the cd2 receptor (knowles, 1989). - ROCHMSD (Additional S&H or Hazmat Fees May Apply)