Roche Diagnostics Corporation Pd-1 (Nat105) Pab, Cell Marque

Roche Diagnostics Corporation pd-1 (nat105) primary ab; programmed death-1 (pd-1) is a member of the cd28 family of receptors that includes cd28, cytotoxic t-lymphocyte-associated antigen 4 (ctla-4), inducible costimulator (icos), and b- and t-lymphocyte attenuator. these receptors play a role in the cellular immune response. for example, cd28 serves as a costimulatory receptor that enhances t-cell activation, whereas ctla-4 serves as an inhibitor of t-cell activation. pd-1 also has an inhibitory function on t cells and b cells, and is important in peripheral tolerance. there are at least 2 ligands for pd-1, pd-l1, and pd-l2, which are expressed on a range of cells. - ROCHMSD (Additional S&H or Hazmat Fees May Apply)