Cell Signaling Inos (D6b6s) Rabbit mAb (Pe Conjugate)

Name: Cell Signaling Inos (D6b6s) Rabbit mAb (Pe Conjugate)
SKU: CSIG-14792S
Price: 454.50 USD

List Price $454.50 Your Price $454.50

Cell Signaling Inos (D6b6s) Rabbit mAb (Pe Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-14792S

MFG.PART: 14792S

UNSPSC: 41116124

Manufacturer: Cell Signaling

Description

Size	100 µl (50 tests)
Reactivity	M
Sensitivity	Endogenous
Source/Isotype	Rabbit IgG
Application/Dilution	{Flow Cytometry (Fixed/Permeabilized): 1:50}
Storage	Supplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/ml BSA. Store at 4°C. Do not aliquot the antibodies. Protect from light. Do not freeze.
Specificity/Sensitivity	iNOS (D6B6S) Rabbit mAb (PE Conjugate) recognizes endogenous levels of total iNOS protein. This antibody does not cross-react with other NOS proteins.
Species Reactivity	Mouse
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly1133 of mouse iNOS protein.
Background	Nitric Oxide Synthase (NOS) catalyzes the formation of nitric oxide (NO) and citrulline from L-arginine, oxygen, and cofactors. Three family members have been characterized: neuronal NOS (nNOS), which is found primarily in neuronal tissue; inducible NOS (iNOS), which is induced by interferon gamma and lipopolysaccharides in the kidney and cardiovascular system; and endothelial NOS (eNOS), which is expressed in blood vessels (1). NO is a messenger molecule with diverse functions throughout the body, including the maintenance of vascular integrity, homeostasis, synaptic plasticity, long-term potentiation, learning, and memory (2,3).

Specifications