We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Sigma-Aldrich Methotrexate Hydrate
List Price $264.48 Your Price $264.48
Sigma-Aldrich Methotrexate Hydrate - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-06563-100MG
MFG.PART: 06563-100MG
UNSPSC: 12352202
Manufacturer: Sigma-Aldrich
biological source
synthetic
Quality Level
200
assay
≥99.0% (sum of enantiomers, HPLC)
form
powder or crystals
optical activity
[α]/D +21.0±2.0°
impurities
≤0.1% sulfated ash
mp
185-204 °C
solubility
water: insoluble
storage temp.
−20°C
SMILES string
[H]O[H].CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Looking for similar products? Visit Product Comparison Guide
Application
Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis.
Other Notes
Folic acid antagonist. Potent inhibitor of dihydrofolate reductase.[1]
pictograms
GHS06,GHS08
signalword
Danger
hcodes
H301,H341,H360D,H372
pcodes
P202 - P260 - P264 - P280 - P301 + P310 - P405
Hazard Classifications
Acute Tox. 3 Oral - Muta. 2 - Repr. 1B - STOT RE 1
target_organs
Liver,Bone marrow
wgk_germany
WGK 3
PPE
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
| SKU | SIAL-06563-100MG |
|---|---|
| Supplier Part Number | 06563-100MG |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | Sigma-Aldrich |
| Temperature | -20C |
| Refrigerated-Frozen | Y |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| Hazardous | Y |
| CAS Number | 133073-73-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |