Sigma-Aldrich Serum, 500mg

Sigma-Aldrich Serum, 500 mg Net Content, Lyophilized Powder Form, Off-White to Light Yellow to Light Brown, 2 to 8 deg C, >=99% Agarose Gel Electrophoresis. Albumin is the most abundant protein in blood plasma, produced in the liver. Albumin is a known carrier of fatty acids (FA). Thus control over specific FAs for cell culture is important, as different cell lines can differ in their sensitivity to particular fatty acids. Fatty acid-free human serum albumin (HSA) is therefore useful for cell culture studies where specific fatty acid content must be strictly controlled, SO that researchers can use particular fatty acids specific to their cell lines. Fatty acid-free albumin also allows for optimal and maximum binding sites for using specific fatty acids in cell culture. The use of FA-free HSA also addresses concerns about endogenous FAs potentially in non-FA-free HSA. Albumin is the most copious plasma protein in humans. Albumin turnover is seen in infants with iron deficiency anemia. Serum albumin is a reliable prognostic indicator in liver disease. Oxidative damage of albumin is associated with advanced liver disease. Albumin is widely used as a blocking agent in immunoassays and immunodetection procedures and as a carrier protein for dilution of antibodies. Awareness of potential trace endogenous content of globulins/IgG in human serum albumin (HSA) is therefore important, because such trace globulins/IgG may serve as antigens for secondary antibodies in immunodetection work. This product undergoes testing for low globulin content/status as essentially globulin-free - SIAL (Additional S&H Or Hazmat Fees May Apply)