Cell Signaling Pank2 (D11e2) Rabbit mAb (Mouse Specific)

Name: Cell Signaling Pank2 (D11e2) Rabbit mAb (Mouse Specific)
SKU: CSIG-12479S
Price: 354.51 USD

List Price $354.51 Your Price $354.51

Cell Signaling Pank2 (D11e2) Rabbit mAb (Mouse Specific) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-12479S

MFG.PART: 12479S

UNSPSC: 12352300

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	M
Sensitivity	Endogenous
Molecular Weight (kDa)	49
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:50}
Storage	Supplied in 10 mm sodium HEPES (pH 7.5), 150 mm NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	PANK2 (D11E2) Rabbit mAb recognizes endogenous levels of total PANK2 protein.
Species Reactivity	Mouse
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu76 of mouse PANK2 protein.
Background	PANK2, pantothenate kinase 2, catalyzes the first step in CoA biosynthesis (1,2). Human PANK2 is located in the mitochondria, and research studies have shown some mutations in human PANK2 are linked to neurodegeneration (2). Alternatively, mouse PANK2 localizes in the cytosol, and defective PANK2 in mice leads to retinal degeneration (1,3).

Specifications