Cell Signaling Fabp3 (A7) Mouse mAb

Name: Cell Signaling Fabp3 (A7) Mouse mAb
SKU: CSIG-14780S
Price: 339.36 USD

List Price $339.36 Your Price $339.36

Cell Signaling Fabp3 (A7) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-14780S

MFG.PART: 14780S

UNSPSC: 12352300

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	14
Source/Isotype	Mouse IgG1
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:100}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	FABP3 (A7) Mouse mAb recognizes endogenous levels of total FABP3 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human FABP3 protein.
Background	Fatty acid binding proteins (FABPs) are cytoplasmic lipid chaperones that bind fatty acids and lipids for transport to various cellular components (1,2). Research studies demonstrate differential FABP expression in several types of tumors and their normal-cell counterparts (3). Fatty acid binding protein 3 (FABP3) is predominantly expressed in heart, skeletal muscle, brain, and mammary gland (4). FABP3 may play a role in supplying energy to the heart and other tissues (5). The release of FABP3 from the heart upon infarction is used as a serum marker for myocardial stress and cardiotoxicity (6). Additional studies suggest that FABP3 is a potential tumor suppressor in breast cancer (7).

Specifications