Beckman Cd1c-Pc5.5, L161, 0.5 Ml, Asr

Beckman the cd1c antigen (also called bdca-1) is a member of the cd1 family of proteins that are structurally related to mhc class i proteins. cd1c is a membrane glycoprotein with a molecular weight of 43 kda, non-covalently associated with β2-microglobulin. cd1c antigen is expressed on a major subpopulation of human myeloid dendritic cells. in blood, cd1c is also expressed on a subpopulation of cd19+ small resting b lymphocytes. its expression has also been detected on cortical thymocytes (weakly), on langerhans cells and on dendritic cells. cd1c+ myeloid dendritic cells have been designated as type-1 myeloid dendritic cells (mdc1s). it has been reported that cd1c is also expressed on mature t cells in a tightly regulated manner. cd1c is involved in antigen-presentation of glycolipids. it may also act in t cells as an immune regulatory molecule. - BKMPFZ (Additional S&H Or Hazmat Fees May Apply)