Sigma-Aldrich Propanephosphonic Acid Anh

Vapor Pressure

97 hPa ( 20 °C)

Quality Level

200

Form

liquid

Bp

77 °C/1013 hPa (ethyl acetate)

Transition Temp

flash point -4 °C (ethyl acetate)

Density

1.08 g/cm³at 20 °C

Storage Temp.

2-8°C

Related Categories

Amino Acids, Resins & Reagents for Peptide Synthesis

Application

• Cyclization of Linear Tetrapeptides Containing N‐Methylated Amino Acids:The study reports the synthesis of naturally occurring cyclotetrapeptides using 1-propanephosphonic acid anhydride, noting unexpected findings in cyclization patterns. (Zhang et al., 2017).

Analysis Note

Assay (T3P) (NMR): ≥ 40.0 %
Pyropropanephosphonic acid (NMR): ≤ 10.0 %
Propanephosphonic acid (NMR): ≤ 0.50 %
Ethyl acetate (calculated): ≤ 50.0 %

Pictograms

GHS02,GHS05,GHS07

Signalword

Danger

Hcodes

H225 - H290 - H314 - H317 - H336

Pcodes

P210 - P233 - P234 - P280 - P303 + P361 + P353 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Target_Organs

Respiratory system

Storage Class

3 - Flammable liquids

Wgk_Germany

WGK 1

Flash_Point_F

24.8 °F - ethyl acetate

Flash_Point_C

-4 °C - ethyl acetate