Sigma-Aldrich Fmpb Am Resin Novabiochem(

Quality Level

200

Product Line

Novabiochem^®

Form

beads

Reaction Suitability

reaction type: Fmoc solid-phase peptide synthesis

Manufacturer/Tradename

Novabiochem^®

Application(S)

peptide synthesis

Functional Group

aldehyde

Storage Temp.

2-30°C

Related Categories

Amino Acids, Resins & Reagents for Peptide Synthesis

General Description

This support is an excellent tool for the production of C-terminal secondary amides. Primary amines can be loaded onto the resin by reductive amination. Following standard Fmoc SPPS, treatment with TFA releases the peptide secondary amides.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Application

• Structural and functional cell and organelle mimics:Utilizes FMPB AM resin in the solid-phase peptide synthesis for specific functionalities in cell and organelle mimics, detailing the chemical modification processes involved. (RJRW Peters, 2015).

Linkage

Replaces: 01-64-0209

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined by elemental analysis of sulfur after derivatization with tosylhydrazide): 0.80 - 1.10 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly (styrene - 1% DVB), 100 - 200 meshNovabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany