Sigma-Aldrich Zic-Hilic Guard Kit Peek 2

Material

PEEK-lined stainless steel column

Quality Level

100

Agency

suitable for USP L114

Product Line

SeQuant^®

Feature

endcapped: no

Packaging

pkg of 3 column

Parameter

550 bar pressure
70 °C max. temp.

Technique(S)

LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable
mass spectrometry (MS): suitable (High)

Column L × I.D.

2 cm × 2.1 mm

Matrix

fully porous particle

Related Categories

HPLC Columns

General Description

The SeQuant^®ZIC^®-HILIC Guard column protects your analytical column from contamination. The guard column kit contains 3 Guard columns including the coupler.
SeQuant® ZIC®-HILIC Columns are designed to retain and separate all types of polar and hydrophilic compounds and for robust chromatography with high selectivity and reproducibility.
The silica-based ZIC^®-HILIC sorbent has a bonded stationary phase consisting of a highly polar, permanent zwitterion. Separation selectivity is favored by the 1:1 zwitterion charge balance, which makes the ZIC^®-HILIC Column overall neutral, with weak, but important, ionic interactions. Tuning of the selectivity on the ZIC^®-HILIC Column during method development is facilitated by the pH-inpendent permanent zwitterion, ensuring that only the analytes (and not the column) are affected during eluent optimization.
Thanks to their favorable retention and robust performance, SeQuant^®HILIC columns have become extremely popular in numerous laboratories around the world. For example, US FDA (United States Food and Drug Administration) has recommended SeQuant^®ZIC^®-HILIC for analysis of melamine and related substances.
SeQuant^®HILIC columns excel in stability and low bleed. These features make them particularly suitable for LC-MS applications where high background can lead to signal suppression and interference with quantitative measurements while also increasing instrument wear. Their high stability makes these high-performance HILIC columns also attractive for traditional HPLC applications.
Learn more about the Supelco HPLC Column portfolio and Method development:
Brochure: HPLC and UHPLC Column Selection Guide
Brochure: A Practical Guide to HPLC - Method Development GuideSeQuant is a registered trademark of Merck KGaA, Darmstadt, GermanyZIC is a registered trademark of Merck KGaA, Darmstadt, GermanyZIC-HILIC is a trademark of Merck KGaA, Darmstadt, Germany