Sigma-Aldrich Superspher(R) 100 RP-18 En

Product Name

Superspher^®100 RP-18 endcapped (4µm) LiChroCART^®125-3, suitable for HPLC

Material

stainless steel column

Agency

suitable for USP L1

Product Line

Superspher^®

Feature

endcapped

Parameter

250 bar pressure
60 °C max. temp.

Technique(S)

HPLC: suitable
mass spectrometry (MS): suitable (Low - Medium)

Column L × I.D.

12.5 cm × 3 mm

Matrix

fully porous particle

Matrix Active Group

C18 bonding phase

Related Categories

HPLC Columns

General Description

HPLC cartridge

Application

• Determination of Retinol and Retinyl Esters in Human Plasma:The Superspher 100 RP-18 endcapped (4 micro M) LiChroCART 125-3 column was employed to achieve precise separations in plasma analysis, demonstrating its efficacy in clinical research settings (Hartmann et Al., 2001).


• Determination of NMDA Receptor NR2B Subunit Blocker in Biological Samples:This study utilized the column for the sensitive detection of neurological drugs across various species, underlining the column′s versatility in pharmacological research (Wyss et Al., 2000).


• Enantioselective Analysis of Ketoprofen Glucuronidation:Highlighting the column′s application in chiral drug metabolism studies, this research focused on the pharmacokinetics of ketoprofen, a nonsteroidal anti-inflammatory drug (Chakir et Al., 1994).


• Glutathione Quantification in Cultured Cells:The column facilitated rapid and accurate measurements of glutathione, a critical antioxidant, enhancing research in cellular health and oxidative stress (Leroy et Al., 1993).

LICHROCART is a registered trademark of Merck KGaA, Darmstadt, GermanySuperspher is a registered trademark of Merck KGaA, Darmstadt, Germany