Sigma-Aldrich Fmoc-Nh-(PEG)₂-Cooh

Quality Level

200

Product Line

Novabiochem^®

Assay

≥92% (TLC)
≥92.0% (HPLC)

Form

powder

Reaction Suitability

reaction type: Pegylations

Manufacturer/Tradename

Novabiochem^®

Application(S)

peptide synthesis

Functional Group

Fmoc

Storage Temp.

2-8°C

Related Categories

Amino Acids, Resins & Reagents for Peptide Synthesis

General Description

Fmoc-NH-(PEG)₂-COOH is a bifunctional 20 atom PEG spacer. It can be introduced using standard coupling methods, such as PyBOP^®, HBTU or TBTU, and is compatible with standard TFA cleavage protocols.

Literature references

B. Baumeister, et Al. (2003)Biopolymers,71, 339.
V. Kumar & J. Aldrich (2003)Org. Lett.,5, 613.
E. Agner, et Al. in ′Peptides 2000, Proc. 26th European Peptide Symposium′, Paris, J. Martinez & J.-A- Fehrentz, 2001, PP. 1011.

Application

Fmoc-NH-(PEG)₂-COOH (20 atoms) Novabiochem^®. CAS 916585-44-9, molar mass 558.62 g/mol.

Linkage

Replaces: 01-63-0141

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(0110)): ≥ 92 %
Assay (HPLC, area%): ≥ 92.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^®products please click here.Novabiochem is a registered trademark of Merck KGaA, Darmstadt, GermanyPyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany