Sigma-Aldrich Fmoc-Lys(Me₃Cl)-Oh N

Quality Level

200

Product Line

Novabiochem^®

Assay

≥95% (TLC)
≥95.0% (HPLC)

Form

powder

Reaction Suitability

reaction type: Fmoc solid-phase peptide synthesis

Manufacturer/Tradename

Novabiochem^®

Application(S)

peptide synthesis

Functional Group

amine

Storage Temp.

2-8°C

Inchi

1S/C24H30N2O4.ClH/c1-26(2,3)15-9-8-14-22(23(27)28)25-24(29)30-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21;/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H-,25,27,28,29);1H/t22-;/m0./s1

Related Categories

Amino Acids, Resins & Reagents for Peptide Synthesis

General Description

A novel derivative for the introduction of trimethyl-lysine during Fmoc SPPS. Ref contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.


Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS

Literature references

S. Rothbart, et Al. (2012)Methods Enzymol.,512, 107.

Linkage

Replaces: 04-12-1270

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 mL DMF): clearly soluble
LC/MS: passes test

To see the solvent systems used for TLC of Novabiochem^®products please click here.Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany