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Sigma-Aldrich (R)-(−)-3-Amino-1-Boc-piperidine
List Price $326.55 Your Price $326.55
Sigma-Aldrich (R)-(-)-3-Amino-1-Boc-Piperidine >=98.0% Tlc - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-07858-1G-F
MFG.PART: 07858-1G-F
UNSPSC: 12352000
Manufacturer: Sigma-Aldrich
Quality Level
100
assay
≥98.0% (TLC)
optical activity
[α]/D -28.5±2°, c = 1 in DMF
SMILES string
CC(C)(C)OC(=O)N1CCC[C@@H](N)C1
InChI
1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChI key
AKQXKEBCONUWCL-MRVPVSSYSA-N
Related Categories
Chiral Catalysts & Ligands
General description
(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.[1]
Application
(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.[2]
pictograms
GHS07
signalword
Warning
hcodes
H302,H315,H319,H335
pcodes
P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
wgk_germany
WGK 3
PPE
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
| SKU | SIAL-07858-1G-F |
|---|---|
| Supplier Part Number | 07858-1G-F |
| UM | EA |
| UNSPSC | 12352000 |
| Manufacturer | Sigma-Aldrich |
| Temperature | room temp |
| Refrigerated-Frozen | N |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| Hazardous | Y |
| CAS Number | 188111-79-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |