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Sigma-Aldrich O-(Benzotriazol-1-Yl)-N N
List Price
$111.30
Your Price
$111.30
Sigma-Aldrich O-(Benzotriazol-1-Yl)-N N N N-Tetramethyluronium Hexagluorophosphate >=98.0% T - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
SIAL-12804-5G-F
MFG.PART:
12804-5G-F
UNSPSC:
12352000
Manufacturer:
Sigma-Aldrich
Quality Level
200
assay
≥98.0% (T)
form
solid
reaction suitability
reaction type: Coupling Reactions
mp
200 °C (dec.) (lit.)
solubility
acetonitrile: 0.1 g/mL, clear
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
F[P-](F)(F)(F)(F)F.CN(C)C(\On1nnc2ccccc12)=[N+](/C)C
InChI
1S/C11H16N5O.F6P/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1
Related Categories
Amino Acids, Resins & Reagents for Peptide Synthesis
General description
HBTU is a peptide coupling agent used in Fmoc-based solid-phase peptide synthesis.[1]
Application
HBTU is a peptide coupling agent for peptide synthesis.[2] It has also been used in standard Fmoc-based solid-phase peptide synthesis (SPPS) protocol.[3]
Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound; Coupling reagent for peptide synthesis; advantages are: very low racemization, simple reaction conditions, very short reaction time, and high yields.
pictograms
GHS07
signalword
Warning
hcodes
H317
pcodes
P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
Hazard Classifications
Skin Sens. 1A
wgk_germany
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
| SKU | SIAL-12804-5G-F |
|---|---|
| Featured | No |
| Supplier Part Number | 12804-5G-F |
| UM | EA |
| UNSPSC | 12352000 |
| Manufacturer | Sigma-Aldrich |
| Temperature | 2-8C |
| Refrigerated-Frozen | Y |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| Hazardous | Y |
| CAS Number | 94790-37-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |