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GenScript Pdgf-Bb, Human; 1mg
List Price $2,920.00 Your Price $2,920.00
GenScript Pdgf-Bb, Human1mg - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-Z03707-1
MFG.PART: Z03707-1
UNSPSC: 12352204
Manufacturer: GenScript USA Inc
Product Introduction
| Species | Human | |
| Protein Construction |
| |
| Purity | ≥ 98% as analyzed by SDS-PAGE | |
| Endotoxin Level | ≤ 0.2 EU/μg of protein by gel clotting method | |
| Biological Activity | Measured in a cell proliferation assay using BALB/c 3T3 cells, the ED50 for this effect is less than 10 ng/ml | |
| Expression System | E. coli | |
| Theoretical Molecular Weight | 24.8 kDa | |
| Apparent Molecular Weight | ~25 kDa, on SDS-PAGE under non-reducing conditions. | |
| Formulation | Lyophilized from a 0.2 μm filtered solution in 20 mM NaAc-HAc, pH 4.5. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | Platelet-derived growth factor (PDGF) presenting in serum but absent from plasma was first discovered in animal study by Lynch and co-workers in the late 1980s. It is a disulfide-linked dimer consisting of two peptides-chain A and chain B. PDGF has three subforms: PDGF-AA, PDGF-BB, PDGF-AB. It is involved in a number of biological processes, including hyperplasia, embryonic neuron development, chemotaxis, and respiratory tubule epithelial cell development. The function of PDGF is mediated by two receptors (PDGFR-α and PDGFR-β). |
| Synonyms | PDGFBB; PDGF-BB |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03707-1 |
|---|---|
| Supplier Part Number | Z03707-1 |
| UM | EA |
| UNSPSC | 12352204 |
| Manufacturer | GenScript USA Inc |
| Temperature | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |